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Lessons from Large-Scale Neurophysiology in the Primate Brain

Abstract

Recent advances in neuronal recording technology have facilitated the development of large-scale, high-density microelectrode arrays resulting in a substantial increase in the number of neurons that can be studied simultaneously within a localized area of neural tissue. This technology has transformed neurophysiological studies, first in rodent models and now in both nonhuman primates and human participants. I will first talk about these recent developments, both their quantitative and qualitative benefits. Next, I will describe some recent work utilizing large-scale electrophysiology to address the short-term coding of remembered stimuli. Lastly, I will discuss newer approaches that leverage the benefits of large-scale neurophysiological recordings.

Biography

Tirin Moore grew up in the San Francisco Bay Area. He received his Ph.D. from Princeton University where he worked with Charles Gross. He was then a postdoctoral fellow at M.I.T., where he worked with Peter Schiller. He started his own laboratory at Stanford University in 2003, where he is currently the Ben Barres Professor of Neurobiology and a Howard Hughes Medical Institute investigator. Professor Moore is a visual neuroscientist who studies neural mechanisms of visual perception, visual-motor integration, and the neural basis of cognition (e.g. attention). For his work on mechanisms of visual attention, Professor Moore received the Troland Research Award and the Pradel Research Award, both from the National Academy of Sciences, and the Golden Brain Award from the Minerva Foundation. He is a member of the American Academy of Arts and Sciences, the National Academy of Medicine, and the National Academy of Sciences.