1.0Faculty of Science Profiles/science/profilesgotcheva/science/profiles/author/gotcheva/rich600338<blockquote class="wp-embedded-content" data-secret="ahMXFtz6Vw"><a href="/science/profiles/faculty/vivian-saridakis/">Vivian Saridakis</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="/science/profiles/faculty/vivian-saridakis/embed/#?secret=ahMXFtz6Vw" width="600" height="338" title="“Vivian Saridakis” — Faculty of Science Profiles" data-secret="ahMXFtz6Vw" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script type="text/javascript"> /* <![CDATA[ */ /*! This file is auto-generated */ !function(d,l){"use strict";l.querySelector&&d.addEventListener&&"undefined"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!/[^a-zA-Z0-9]/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret="'+t.secret+'"]'),o=l.querySelectorAll('blockquote[data-secret="'+t.secret+'"]'),c=new RegExp("^https?:$","i"),i=0;i<o.length;i++)o[i].style.display="none";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute("style"),"height"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):"link"===t.message&&(r=new URL(s.getAttribute("src")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener("message",d.wp.receiveEmbedMessage,!1),l.addEventListener("DOMContentLoaded",function(){for(var e,t,s=l.querySelectorAll("iframe.wp-embedded-content"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute("data-secret"))||(t=Math.random().toString(36).substring(2,12),e.src+="#?secret="+t,e.setAttribute("data-secret",t)),e.contentWindow.postMessage({message:"ready",secret:t},"*")},!1)))}(window,document); //# sourceURL=/science/profiles/wp-includes/js/wp-embed.min.js /* ]]> */ </script> Research Focus The attachment of ubiquitin to target proteins plays important regulatory tasks in eukaryotic cellular processes. The most studied after effect of ubiquitination is the subsequent degradation of the target protein by the 26S proteasome. Degradation of cellular proteins has many regulatory effects including cell cycle progression, stress response, signal transduction, transcriptional activation and […]